An efficient route for the synthesis of a new class of pyrido[2,3-d]pyrimidine derivatives.

نویسندگان

  • Shujiang Tu
  • Junyong Zhang
  • Runhong Jia
  • Bo Jiang
  • Yan Zhang
  • Hong Jiang
چکیده

A new reaction of 4-arylidene-3-methylisoxazol-5(4H)-one or 4-arylidene-2-phenyloxazol-5(4H)-one with 2,6-diaminopyrimidin-4(3H)-one is described and a number of new pyrido[2,3-d]pyrimidine-4,7-dione derivatives are synthesized. This protocol has the advantages of good yields, broad substrate scope and simple work-up.

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 5 9  شماره 

صفحات  -

تاریخ انتشار 2007